Mechanism of Action

GSH, an endogenous antioxidant, has the function of fighting against free radicals to prevent oxidative stress, removing the toxicity of chemotherapy drugs, participating in the γ-glutamyl cycle to facilitate protein synthesis and providing the sulfhydryl to maintain enzyme activities.

Mechanism in liver disease

In a patient with liver disease, the liver cells incur damage, and the GSH concentration within liver cells decreases dramatically, resulting in the decrease of anti-oxidation capability of liver cells. In such a case, the immune function of human body decreases, and the damage of liver cells increases sharply. Exogenous GSH can effectively block the oxidative stress, eliminating the harmful factors and protecting the liver.

Mechanism in chemotherapy on tumor

Most of the cell damages caused by chemotherapy drugs occur to liver. The toxic metabolites (including free radicals, electrophile, oxygen base, etc.)
of the chemotherapy drugs also cause cell death ...more