Distribution in tissues and cells

In mammalian tissues

Among all the organs in the body, GSH has the highest concentration in liver, the organ responsible for anti-oxidation and detoxification.

In eukaryotic cells

GSH mainly distributes in cells, with most of which in cytoplasm and only a small percentage existing in mitochondria. GSH in mitochondria plays an important role in cell functions.

Importance of the supply of exogenous GSH

Reduced glutathione plays an essential role in the anti-oxidation system of our body. Normal liver tissues contain sufficient amount of reduced glutathione. However, in the case of liver cell damage, the concentration of GSH in liver decreases sharply, the GSH level in blood cells drops accordingly, and the MDA (malondialdehyde) level in blood cells increases significantly. All of these indicate that the anti-oxidation capability of the blood decreases, the immunity declines and liver cells damage increases. In such a situation, supply of exogenous GSH (Lutasun) can substantially increase the GSH level in liver cells, facilitating the removal of the harmful factors and the protection of the liver.